1. 個人簡介:
楊仕平博士,教授,無機化學與生物化工專業碩士生導師,環境化學博士生導師。
郵箱:shipingy@shnu.edu.cn
教育經曆:
1997-2000,博士,中山大學
1991-1994,碩士,鄭州大學
工作經曆:
2004-至今,上海師範大學教授
2002-2004,上海師範大學副教授
2000-2002,華南農業大學博士後
2. 主要研究方向:
生物無機化學、納米材料生物應用以及功能配合物應用。主要以多功能材料為平台,開發面對腫瘤精準醫療的影像探針和診療一體化試劑。
[1] 磁、光納米材料在醫學成像、水處理,特别是在疾病的早期診斷上的應用;
[2] 磁傳感器及其在過渡金屬離子、生物大分子和微生物學等方面的應用;
[3] 咪唑基團配位聚合物及其納米材料的結構分析和應用。
3. 代表性科研項目:
[1] 基于超小Fe@Fe3O4納米粒子的T1磁共振成像研究,國家自然科學基金(面上項目),2017-2020。
[2] 基于Gd标記的磁性納米粒子的合成及其在腫瘤靶向MRI中的應用,國家自然科學基金(面上項目),2013-2016。
[3] 重金屬離子檢測的磁性微球開發,上海市科委科技攻關項目,2013-2016。
[4] 基于PAMAM 原位修飾的功能化鐵酸錳的合成及其在分子影像中的應用,國家自然科學基金(面上項目),2010-2012。
4. 代表性論文及著作:
[1] Lu An, Xiaodong Wang, Xichuan Rui, Jiaomin Lin, Hong Yang, Qiwei Tian*, Cheng Tao, Shiping Yang*. In situ sulfidation of Cu2O by endogenous H2S for colon cancer theranostics. Angewandte Chemie (International ed. in English), 2018.
[2] Lu An, Chenglin Yan, Xueling Mu, Cheng Tao, Qiwei Tian*, Jiaomin Lin, Shiping Yang*. Paclitaxel-Induced Ultrasmall Gallic Acid-Fe@BSA Self-Assembly with Enhanced MRI Performance and Tumor Accumulation for Cancer Theranostics. ACS Appl. Mater. Interfaces, 2018, 10 (34), 28483-28493.
[3] Qunfeng Feng, Yanjun Xu, Bing Hu, Lu An, Jiaomin Lin, Qiwei Tian*, Shiping Yang*. A smart off-on copper sulfide photoacoustic imaging agent based on amorphous-crystalline transition for cancer imaging. Chem. Commun., 2018, 54 (78), 10962-10965.
[4] Ping Zhou, Heng Zhao, Quan Wang, Zhiguo Zhou*, Jing Wang, Guang Deng, Xiyou Wang, Qian Liu, Hong Yang, Shiping Yang*. Photoacoustic-Enabled Self-Guidance in Magnetic-Hyperthermia Fe@Fe3O4 Nanoparticles for Theranostics In Vivo. Advanced Healthcare Materials, 2018, 7 (9).
[5] Heng Zhao, Ping Zhou, Kai Huang, Guang Deng, Zhiguo Zhou*, Jing Wang, Mingwei Wang, Yingjian Zhang*, Hong Yang, Shiping Yang*. Amplifying Apoptosis Homing Nanoplatform for Tumor Theranostics. Advanced Healthcare Materials, 2018, 7 (14).
[6] Jing Wang, Heng Zhao, Zhiguo Zhou*, Ping Zhou, Yuping Yan, Mingwei Wang*, Hong Yang, Yingjian Zhang, Shiping Yang*. MR/SPECT Imaging Guided Photothermal Therapy of Tumor-Targeting Fe@Fe3O4 Nanoparticles in Vivo with Low Mononuclear Phagocyte Uptake. ACS Appl. Mater. Interfaces, 2016, 8 (31), 19872-19882.
[7] Hao Zhang, Huixia Wu*, Jun Wang, Yan Yang, Dongmei Wu, Yingjian Zhang, Yang Zhang, Zhiguo Zhou, Shiping Yang*, Graphene oxide-BaGdF5 nanocomposites for multi-modal imaging and photothermal therapy. Biomaterials 2015, 42, 66-77.
[8] Hong Yang, Changyuan Qin, Chao Yu, Yang Lu, Hongwei Zhang, Fengfeng Xue, Dongmei Wu, Zhiguo Zhou, Shiping Yang*. RGD-Conjugated Nanoscale Coordination Polymers for Targeted T-1- and T-2-weighted Magnetic Resonance Imaging of Tumors in Vivo. Adv. Funct. Mater., 2014, 24 (12), 1738-1747.
[9] Lu An, He Hu*, Jing Du, Jie Wei, Li Wang, Hong Yang, Dongmei Wu, Haili Shi, Fenghua Li, Shiping Yang*. Paramagnetic hollow silica nanospheres for in vivo targeted ultrasound and magnetic resonance imaging. Biomaterials, 2014, 35 (20), 5381-5392.
[10] Zhiguo Zhou, Yanan Sun, Jinchao Shen, Jie Wei, Chao Yu, Bin Kong, Wei Liu, Hong Yang, Shiping Yang*, Wei Wang*. Iron/iron oxide core/shell nanoparticles for magnetic targeting MRI and near-infrared photothermal therapy. Biomaterials, 2014, 35 (26), 7470-7478.
5. 獲獎情況:
[1] 上海市自然科學獎三等獎,2018年。
[2] 上海市基礎教育教學成果獎一等獎,2017年。
[3]上海科普教育創新獎三等獎,2015年。
6. 代表性授權專利:
[1] 楊仕平,楊豔,楊紅,疊氮多巴胺和羧基聚乙二醇修飾的Fe/Fe3O4納米粒子及其制備和應用,專利号:ZL201610077270.1
[2] 楊仕平,沈金超,楊紅,周治國,張钖,楊豔,基于Au-Fe3O4複合納米粒子的三聚氰胺雙模式傳感器及制備,專利号:ZL201510155441.3
[3] 楊仕平,孫亞楠,周治國,沈金超,王俊,王力,一種具有光熱功能的Fe@Fe3O4納米粒子及其制備方法和應用,專利号:ZL201310214554.7
[4] 楊仕平,汪娟娟,周治國,陳冬梅,楊昕儀,孔斌,T1-T1協同作用钆螯合四氧化三錳納米粒子的制備方法及其生物應用,專利号:ZL201210452070.1
更新于2018年11月